CN
mRNA
mRNA
mRNA-LNP Process Development
mRNA-LNP Process Development

Mature and Efficient LNP Formulation Process Development Platform

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Our service offerings:
  • Microfluidic Reaction

    Flow rate, flow rate ratio

    N/P

    mRNA concentration

    Lipid concentration

    Aqueous system, salt concentration

  • Ultrafiltration

    Membrane/hollow fiber screening

    Transmembrane pressure and flux, ultrafiltration concentration

    Load

    Diafiltration volume

  • Formulation Development

    Buffer system

    pH

    Drug formulation compatibility

    Compatible materials

  • Process Scale-up and Transfer

    Verification of process consistency with 3 consecutive batches

    Gap analysis between R&D and manufacturing

    Technology transfer protocol determination

Our service offerings:
Service scope:
Service advantages:

 · Advanced LNP process platform

 · Efficient process development and transfer

 · Experienced in R&D to manufacturing process transfer and scale-up

Key Equipment:
  • Microfluidic reaction system
  • AKTA flux TFF system
  • Biological Safety Cabinet