Asymchem Boston Corporation 10 Gill Street, Suite J Woburn, MA 01801
+86 (021)60272068
MKT@asymchem.com.cn
Mature and Efficient LNP Formulation Process Development Platform
Flow rate, flow rate ratio
N/P
mRNA concentration
Lipid concentration
Aqueous system, salt concentration
Membrane/hollow fiber screening
Transmembrane pressure and flux, ultrafiltration concentration
Load
Diafiltration volume
Buffer system
pH
Drug formulation compatibility
Compatible materials
Verification of process consistency with 3 consecutive batches
Gap analysis between R&D and manufacturing
Technology transfer protocol determination
· Advanced LNP process platform
· Efficient process development and transfer
· Experienced in R&D to manufacturing process transfer and scale-up