In Vitro mRNA Transcription Process Development

Comprehensive and efficient in vitro transcription process development platform

Our service offerings:
Our service offerings:
Service scope:
Service advantages:

  · Two mature mRNA drug substance platforms: co-transcriptional capping and post-transcription capping

  · For mRNA of different lengths and GC content, the platform process can achieve a yield of 9.0-11.0 mg/mL IVT

  · Advanced Oligo dT purification platform, with a variety of Oligo dT resins available

  · Process development can be completed in 4 weeks, and process qualification and technology transfer can be completed in 2 weeks

Key Equipment:
  • Thermostatic reactor
  • AKTA chromatography
  • TFF system
  • Biological Safety Cabinet